Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib
IJMS | Free Full-Text | MLN4924, a Protein Neddylation Inhibitor, Suppresses the Growth of Human Chondrosarcoma through Inhibiting Cell Proliferation and Inducing Endoplasmic Reticulum Stress-Related Apoptosis
The MLN4924 inhibitor exerts a neuroprotective effect against oxidative stress injury via Nrf2 protein accumulation - ScienceDirect
Figure 5 | Targeting the Neddylation Pathway to Suppress the Growth of Prostate Cancer Cells: Therapeutic Implication for the Men's Cancer
Cancers | Free Full-Text | Targeting NEDDylation as a Novel Approach to Improve the Treatment of Head and Neck Cancer
Celecoxib Synergistically Enhances MLN4924-Induced Cytotoxicity and EMT Inhibition Via AKT and ERK Pathways in Human Urothelial Carcinoma - Shida Xiong, Wei Huang, Xiaoqiang Liu, Qian Chen, Yi Ding, Haoxuan Huang, Ru Zhang,
Pevonedistat - an overview | ScienceDirect Topics
Neddylation regulation of mitochondrial structure and functions | Cell & Bioscience | Full Text
MLN4924 specifically inhibits neddylation and suppresses the growth of... | Download Scientific Diagram
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS
The NAE inhibitor pevonedistat (MLN4924) synergizes with TNF-α to activate apoptosis | Cell Death Discovery
Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells | Scientific Reports
Continued ) F, schematic illustration of proposed mechanism underlying... | Download Scientific Diagram
Cardioprotective effect of MLN4924 on ameliorating autophagic flux impairment in myocardial ischemia-reperfusion injury by Sirt1 - ScienceDirect
Mechanism of MLN4924 action. Proposed mechanisms of how MLN4924... | Download Scientific Diagram
Frontiers | Advances in Cancer Treatment by Targeting the Neddylation Pathway
Neddylation Pathway as a Novel Anti-cancer Target: Mechanistic Investigation and Therapeutic Implication | Bentham Science
Cancers | Free Full-Text | Drug Development Targeting the Ubiquitin–Proteasome System (UPS) for the Treatment of Human Cancers
Frontiers | Targeting Cullin-RING E3 Ligases for Radiosensitization: From NEDDylation Inhibition to PROTACs
Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis | Cell Death & Disease
Blockage of neddylation modification stimulates tumor sphere formation in vitro and stem cell differentiation and wound healing in vivo | PNAS
Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells | Scientific Reports
Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy
Pevonedistat - an overview | ScienceDirect Topics
Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression
Model for redox regulation of ENaC where reactive ROS or MLN4924... | Download Scientific Diagram
